If you are a researcher focused on Down syndrome and other intellectual disabilities of genetic origin appearing in early childhood, the Scientific Advisory Board of the Jerome Lejeune Foundation invites you to submit your research project. The Foundation is looking for projects focused on deciphering the pathophysiology of the cognitive deficits of patients, especially those with Down syndrome (trisomy 21) and linked pathologies.
Autumn Versus Spring Requirements
The autumn call for proposals will be exclusively dedicated to Down syndrome research with advanced and pilot/exploratory grants.
The spring call for proposals (from mid-January to early March) will be dedicated to both Down syndrome and other rare intellectual disabilities of genetic origin, such as Fragile X, cri du chat, Rett, Williams-Beuren, Prader-Willi, Angelman, Smith-Magenis and other syndromes, and will not exceed 50% of the total amount of the annual global grant. Autism not linked to above diseases is out of this call for grants.
Scope of Research
Applications could cover fundamental, translational, epidemiological, clinical research, neurobiology, and pharmacology, including animal pharmacology, genetic, genomic, iPSCs, and neuropsychology techniques or data analysis. Priority will be given to clinical research projects.
Two types of research projects may be submitted and will be separately evaluated by the scientific board experts or external reviewers if needed for each call:
- Advanced grants will be dedicated to larger breakthrough projects with preliminary data. The maximum funding will be 80,000.00 € for a maximum of two years (i.e. 40,000.00 € per year for a maximum of two years). Ideally, two to four projects could be funded per call, but it could be more or less.
- Pilot or exploratory grants will be dedicated to initial early stage experiments built on preliminary data, or to ancillary projects to primary larger projects. The maximum funding will be 40,000.00 € for a maximum of two years (i.e. 20,000.00 € per year for a maximum of two years. The number of funded projects will depend of the annual global budget allocated by the Jerome Lejeune Foundation to the calls. Clinical projects could benefit from more funding.
Through this call the Jerome Lejeune Foundation will also support the organization of conferences, workshops and courses. Such projects will also be reviewed by the Scientific Advisory Board.
IMPORTANT: The funds provided by the Jerome Lejeune Foundation cannot in any way be used to purchase or make use of human embryonic or fetal tissues or another biological material obtained through direct abortions, IVF, human cloning, or creation of new human germinal cells. The Jerome Lejeune Foundation does not want to be associated with such work.
It is mandatory that researchers follow their academic and national Good Laboratory Practices (GLP) (i.e. all measures that ensure quality, traceability and integrity of the data during all research.).
For further details, please click on the sample below.
View sample application and requirements
How to Apply
For the autumn call for proposals, please fill out the online application form “JLF Call for grants” before August 10, 2020 at midnight CEST.
Before applying, please read the restrictions regarding the General Data Protection Regulation (GDPR/RGPD). For any request regarding the processing of your personal data, please contact us at the following email address: [email protected]
For any further information relating specifically to the call for grants, please contact:
Fondation Jérôme Lejeune – Conseil Scientifique
37 rue des Volontaires, 75015 Paris
+33 (0)1 5658 5638
Date of provisional Scientific Advisory Board decision: mid-November 2020
Board of Directors final decision: December 2020